Publications

The Centre is proud of its strong publication record, and is dedicated to advancing its field.
  1. Cheung S, Ainslie PN (2021) Advanced Environmental and Exercise Physiology (2nd Edition). ISBN: 9781492593980
  2. Luks AM, Ainslie PN, Lawley JS, Roach RC, Sampson T, (2021) Ward, Milledge and West’s High Altitude Medicine and Physiology (6th Edition). CRC Press. ISBN 9780367001353
  3. Tremblay JC and Ainslie PN (2021) Global and country-level estimates of human population at high altitude. Proc Nat Acad Sci USA, 4;118(18):e2102463118. https://www.pnas.org/content/118/18/e2102463118 DOI: https://doi.org/10.1073/pnas.2102463118
  4. Willie CK, Patrician A, Hoiland RL, Williams A, Gasho C, Subedi P, Anholm J, Drane A, Tymko MM, Flück D, Plato S, McBride M, Francesco G, Binsted G, Eller LK, Reimer RA, MacLeod DM, Stembridge M, Ainslie PN (2021) Influence of iron manipulation on hypoxic pulmonary vasoconstriction and pulmonary reactivity during ascent and acclimization to 5050m. J Physiol, 599(5):1685-1708 https://pubmed.ncbi.nlm.nih.gov/33442904/ DOI: https://doi.org/10.1113/JP281114
  5. Hoiland RL, Caldwell HG, Howe CA, Nowak-Flück D, Stacey BS, Bailey DM, Paton JE, Green DJ, Sekhon MS, Macleod DM, Ainslie PN (2020). Nitric oxide is fundamental to neurovascular coupling in humans. J Physiol, 598(21):4927-4939 https://pubmed.ncbi.nlm.nih.gov/32785972/ DOI: https://doi.org/10.1113/jp280162
  6. Bain AR, Hoiland RL, Donnelly J, Fluck D, Sekhon M, Greiner J. DeSouza CA, Ainslie PN (2020) Cerebral metabolism, pro-oxidation, and pro-inflammation in severe passive heat stress; influence of arterial pH. J Physiol, 598 (5):943-954 https://pubmed.ncbi.nlm.nih.gov/31900940/ DOI: https://doi.org/10.1113/jp278889
  7. Stembridge M, Williams AM, Gasho C, Dawkins TG, Drane A, Villafuerte FC, Levine BD, Shave R, Ainslie PN (2019) The overlooked significance of plasma volume for successful adaptation to high altitude in Sherpa and Andean natives. Proc Nat Acad Sci USA, 116(33):16177-16179 https://pubmed.ncbi.nlm.nih.gov/31358634/ DOI: https://doi.org/10.1073/pnas.1909002116
  8. Hoiland RL, Howe CA, Carter HH, Tremblay JC, Willie CK, Donnelly J, MacLeod DB, Gasho C, Stembridge M, Boulet LM, Niroula S, Ainslie PN (2019) UBC-Nepal expedition: phenotypical evidence for evolutionary adaptation in the control of cerebral blood flow and oxygen delivery at high altitude. J Physiol, 597(12):2993-3008 https://pubmed.ncbi.nlm.nih.gov/31026348/ DOI: https://doi.org/10.1113/jp277596
  9. Smith KJ, Macleod DB, Willie CK, Smith KJ, Lewis NC, Day, TD, Ikeda K, Hoiland RL, Macleod N, Ainslie PN (2014) Influence of high altitude on cerebral blood flow and fuel utilization during exercise and recovery. J Physiol, 15; 5507-27. https://pubmed.ncbi.nlm.nih.gov/25362150/ DOI: https://doi.org/10.1113/jphysiol.2014.281212
  10. Willie CK, Macleod DB, Shaw AD, Smith KJ, Tzeng YC, Eves NE, Ikeda K, Graham J, Lewis NC, Day TA, Ainslie PN (2012) Regional brain blood flow in man during acute changes in arterial blood gases. J Physiol, 15: 3261-75 https://pubmed.ncbi.nlm.nih.gov/22495584/ DOI: https://doi.org/10.1113/jphysiol.2012.228551
  1. Sharma T, Copeland PV, Debenham MIB, Bent LR, Dalton BH. Neuromechanical characterization of the abductor hallucis and its potential role in upright postural control. Appl Physiol Nutr Metab 49: 293-305, 2024.
  2. Debenham MIB, Bruce CD, Rancier JM, McNeil CJ, Dalton BH. Normobaric hypoxia does not influence the sural nerve cutaneous reflex during standing. Exp Brain Res 241: 2683-2692,
  3. Magnuson J, Dalton BH, McNeil CJ. The orderly recruitment of motor units may be modified when a muscle is acting as an antagonist. J Appl Physiol 135: 519-526, 2023.
  4. Debenham MIB, Grantham TDA, Smirl JD, Foster GE, Dalton BH. The effects of acute normobaric hypoxia on vestibular-evoked balance responses in humans. JVR 33: 31-49, 2023.
  5. Debenham MIB, Kang HJ, Cheung SS, Dalton BH. The influence of reduced foot dorsum cutaneous sensitivity on the vestibular control of balance. Eur J Appl Physiol 123: 65-79, 2023.
  6. Paris M, Power GA, McNeil CJ, Rice CL, Dalton BH. Age-related performance fatigability: A comprehensive review of dynamic tasks. J Appl Physiol 133: 850-866, 2022.
  7. Trotman M, Kennefick M, Coughlin S, van Donkelaar P, Dalton BH. The effects of increased cognitive processing on reactive balance control following perturbations to the upper limb. Exp Brain Res 240: 1317-1329, 2022.
  8. Ha PL, Peters WB, McGeehan MA, Dalton BH. Age-related reduction in peak power and increased postural displacement are related to enhanced vestibular-evoked balance responses in females. Exp Gerontol 160: 111670, 2022.
  9. Allen MD, Dalton BH, Gilmore KJ, McNeil CJ, Doherty TJ, Rice CL, Power GA. Neuroprotective effects of exercise on the aging human neuromuscular system. Exp Gerontol 152: 111465, 2021.
  10. Debenham MIB, Smuin J, Grantham TDA, Ainslie PN, Dalton BH. Invited Review: Hypoxia and Standing balance control. Eur J Appl Physiol 121: 993-1008, 2021.
  1. Brunton NM, Barbour D, Gelinas JC, Yacyshyn AF, Sasso JS, Harper MI, McNeil CJ, Eves ND. Lower-Limb Resistance Training Reduces Exertional Dyspnea and Intrinsic Neuromuscular Fatigability in Individuals with COPD. Journal of Applied Physiology, 134(5):1105-1114, 2023.
  2. Wright SP, Dawkins TG, Harper MI, Stembridge M, Shave R, Eves ND. The Mueller Maneuver Attenuates Left Atrial Phasic Volumes and Myocardial Strain in Healthy Younger Adults. Accepted American Journal of Physiology – Heart and Circulatory Physiology. 325(5): H1235-1241, 2023.
  3. Gelinas JC, Harper MI, Sasso JP, Wright SP, Melzer B, Agar G, DuManoir G, Guenette J, Roman M, Rolf JD, Eves ND. Phenotyping Cardiopulmonary Exercise Limitations in Chronic Obstructive Pulmonary Disease. Frontiers in Physiology, https://doi.org/10.3389/fphys.2022.816586, 2022.
  4. Wright SP, Dawkins TG, Eves ND, Shave R, Tedford RJ, Mak S. Hemodynamic Function of The Right Ventricular-Pulmonary Vascular-Left Atrial Unit: Normal Responses To Exercise In Healthy Adults. American Journal of Physiology – Heart and Circulatory Physiology, 2021.
  5. Cheyne WS, Harper MI, Gelinas JC, Sasso JP Eves ND. Mechanical Cardiopulmonary Interactions During Exercise In Health And Disease. Journal of Applied Physiology 128(5)1271-1279, 2020.
  6. Cheyne WS, Gelinas JC, Eves ND. Hemodynamic Effects of Incremental Lung Hyperinflation. American Journal of Physiology – Heart and Circulatory Physiology 315(3): H474-H481, 2018.
  7. Williams AM, Shave RE, Cheyne WS, Eves ND. The Influence of Adrenergic Stimulation on Sex-Differences in Left Ventricular Twist Mechanics. Journal of Physiology, 595(12): 3973-3985, 2017.
  8. Gelinas J, Lewis N, Harper MI, Rolf JD, Eves ND. Aerobic Exercise Training Does Not Alter Vascular Structure and Function in COPD. Experimental Physiology. 102(11): 1548-1560, 2017.
  9. Cheyne WS, Williams AM, Harper MI, Eves ND. Heart-Lung Interaction in a Model of COPD: The Importance of Lung Volume. American Journal of Physiology – Heart and Circulatory Physiology, 311(6): H1367-H1374, 2016.
  10. Williams AM, Shave RE, Stembridge M, Eves ND. Females Have Greater Left Ventricular Twist Mechanics Than Males During Acute Reductions to Preload. American Journal of Physiology – Heart and Circulatory Physiology 311(1):H76-84, 2016.

1. Bird JD, Lance ML, Banser T,Thrall SF, Cotton PD, Lindner JR, Eves ND, Dominelli PB, Foster GE. (2024) Quantifying diaphragm blood flow with contrast-enhanced ultrasound in humans. CHEST. Accepted April 29, 2024.

2. Bird J, Sands SA, Alex R, Shing C, Shafer BM, Jendzjowsky N, Wilson R, Day TA, Foster GE. (2023) Sex related differences in loop gain during high altitude sleep disordered breathing. Annals of the American Thoracic Society. 8: 1192-1200.  

3. Shafer BM, Nardone M, Incognito A, Vermeulen TD, Teixeira A, Millar PJ, Sheel AW, West C, Ayas N, Foster GE. (2023) Acute hypoxia elicits lasting reductions in the sympathetic action potential transduction of arterial blood pressure in males. Journal of Physiology. 601(3); 669-687.

4. Shafer BM, Incognito AV, Vermeulen TD, Nardone M, Teixeira AL, Klassen SA, Millar PJ, Foster GE. (2022) Action potential amplitude and baroreflex resetting of action potential clusters mediate hypoxia-induced sympathetic long-term facilitation. Journal of Physiology. 600(13): 3127-3147.

5. Shafer BM, Incognito AV, Vermeulen TD, Nardone M, Teixeira AL, Benbaruj J, Millar PJ, Foster GE. (2021) Muscle metaboreflex control of sympathetic activity is preserved following acute intermittent hypercapnic hypoxia. Medicine and Science in Sports and Exercise. 53(11): 2233-2244.

6. Vermeulen TD, Benbaruj J, Brown CV, Shafer BM, Floras JS, Foster GE. (2020) Peripheral chemoreceptor contribution to ventilatory long-term facilitation induced by acute intermittent hypercapnic hypoxia in healthy males and females. Journal of Physiology. 598(20): 4713-4730

7. Brown CV, Boulet LM, Vermeulen TD, Sands SA, Wilson RJA, Ayas NT, Floras JS, Foster GE. (2020) Angiotensin II-type-I receptor antagonism does not influence the chemoreceptor reflex or hypoxia-induced central sleep apnea in men. Frontiers in Neuroscience. 14:382.

8. Stuckless TJR, Vermeulen TD, Brown CV, Boulet LM, Shafer BM, Wakeham DJ, Steinback CD, Ayas NT, Floras JS, Foster GE. (2020) Acute intermittent hypoxia and sympathetic neurovascular transduction in men. Journal of Physiology.  598(3): 473-487.

9. Boulet LM, Teppema LJ, Hackett HK, Dominelli PB, Cheyne WS, Dominelli GS, Irwin DC, Buehler PW, Baek JH, Swenson ER, Foster GE. (2018) Attenuation of hypoxic pulmonary vasoconstriction by acetazolamide and methazolamide in humans. J Appl Physiol. 125: 1795-1803.

10. Dominelli PB, McNeil C, Vermeulen TD, Brown C, Stuckless TJR, Dominelli GS, Swenson ER, Teppema LJ, Foster GE. (2018) Effect of acetazolamide and methazolamide on diaphragm and dorsiflexor fatigue: a randomized controlled trial. Journal of Applied Physiology. 125(3): 770-779.

1. Monteyne AJ, Falkenhain K, Whelehan G, Neudorf H, Abdelrahman DR, Murton AJ, Wall BT, Stephens FB, Little JP A ketone monoester drink reduces postprandial blood glucose concentrations in adults with type 2 diabetes: a randomised controlled trial.
Diabetologia. 2024 Jun;67(6):1107-1113. doi: 10.1007/s00125-024-06122-7. Epub 2024 Mar 14. PMID: 38483543Free PMC article.Clinical Trial.

2. Neudorf H, Islam H, Falkenhain K, Oliveira B, Jackson GS, Moreno-Cabañas A, Madden K, Singer J, Walsh JJ, Little JP.
Effect of the ketone beta-hydroxybutyrate on markers of inflammation and immune function in adults with type 2 diabetes. Clin Exp Immunol. 2024 Mar 12;216(1):89-103. doi: 10.1093/cei/uxad138.

3. Marcotte-Chénard A, Tremblay R, Falkenhain K, Little JP, Riesco E.
Effect of Acute and Chronic Ingestion of Exogenous Ketone Supplements on Blood Pressure: A Systematic Review and Meta-Analysis.
J Diet Suppl. 2024;21(3):408-426. doi: 10.1080/19390211.2023.2289961. Epub 2023 Dec 25. PMID: 38145410Review.4.

4. Falkenhain K, Oliveira BF, Islam H, Neudorf H, Cen HH, Johnson JD, Madden K, Singer J, Walsh JJ, Little JP.The effect of acute and 14-day exogenous ketone supplementation on glycemic control in adults with type 2 diabetes: two randomized controlled trials. Am J Physiol Endocrinol Metab. 2024 Jan 1;326(1):E61-E72. doi: 10.1152/ajpendo.00332.2023. Epub 2023 Nov 22. PMID: 37991451

5. Stork MJ, Marcotte-Chénard A, Jung ME, Little JP.Exercise in the workplace: examining the receptivity of practical and time-efficient stair-climbing “exercise snacks”. Appl Physiol Nutr Metab. 2024 Jan 1;49(1):30-40. doi: 10.1139/apnm-2023-0128. Epub 2023 Sep 25. PMID: 37748202

6.Rafiei H, Omidian K, Chang CR, Little JP.Saliva
insulin tracks plasma insulin across the day following high-carbohydrate and low-carbohydrate meals.
Appl Physiol Nutr Metab. 2023 Sep 1;48(9):700-709. doi: 10.1139/apnm-2023-0066. Epub 2023 Jun 1. PMID: 37262929

7. Oliveira BF, Chang CR, Oetsch K, Falkenhain K, Crampton K, Stork M, Hoonjan M, Elliott T, Francois ME, Little JP.Impact of a Low-Carbohydrate Compared with Low-Fat Breakfast on Blood Glucose Control in Type 2 Diabetes: A Randomized Trial. Am J Clin Nutr. 2023 Jul;118(1):209-217. doi: 10.1016/j.ajcnut.2023.04.032. Epub 2023 May 29. PMID: 37257563Clinical Trial.

8. MacKay D, Chan C, Dasgupta K, Dominy C, Gagner M, Jin S, Kim J, Little JP, MacDonald B, McInnes N, Reichert S, Bajaj HS; Remission of Type 2 Diabetes: Diabetes Canada Clinical Practice Guidelines Expert Working Group. Diabetes Canada Clinical Practice Guidelines Steering Committee:; Bajaj HS, Gilbert J, Houlden R, Kim J, MacDonald B, MacKay D, Mansell K, Rabi D, Senior P, Sherifali D. Can J Diabetes. 2022 Dec;46(8):753-761.e8. doi: 10.1016/j.jcjd.2022.10.004. Epub 2022 Nov 11. PMID: 36567079No abstract available.

9. Falkenhain K, Islam H, Little JP.Exogenous ketone supplementation: an emerging tool for physiologists with potential as a metabolic therapy. Exp Physiol. 2023 Feb;108(2):177-187. doi: 10.1113/EP090430. Epub 2022 Dec 19. PMID: 36533967Free PMC article.Review.

10. Falkenhain K, Daraei A, Forbes SC, Little JP.Effects of Exogenous Ketone Supplementation on Blood Glucose: A Systematic Review and Meta-analysis. Adv Nutr. 2022 Oct 2;13(5):1697-1714. doi: 10.1093/advances/nmac036. PMID: 35380602 Free PMC article.

  1. Tallon CM, Nowak-Flück D, Rieger MG, Green DJ, Tremblay MS, Ainslie PN, McManus AM. Exercise breaks prevent attenuation in cerebrovascular function following an acute bout of uninterrupted sitting in healthy children. Experimental Physiology, 2023; 108:1386-1399
  2. McManus AM, Tallon CM. Cerebrovascular responses to exercise. In N. Armstrong and W. Van Mechelen (Eds.) Oxford Textbook of Children’s Sport and Exercise Medicine. Oxford University Press, Oxford. 2023. https://doi.org/10.1093/med/9780192843968.003.0007
  3. Armstrong N, McManus AM.  Cardiopulmonary responses to exercise. In N. Armstrong and W. Van Mechelen (Eds.) Oxford Textbook of Children’s Sport and Exercise Medicine. Oxford University Press, Oxford. 2023. https://doi.org/10.1093/med/9780192843968.003.0010
  4. Rieger MG, Tallon CM, Perkins DR, Smith KJ, Stembridge M, Piombo S, Radom-Aizik S, Cooper DM, Ainslie PN, McManus AM. Cardiopulmonary and cerebrovascular acclimatization in children and adults at 3800 m. Journal of Physiology, 2022; 600(22):4849-4863.
  5. Tallon CM, Talbot JS, Smith KJ, Lewis N, Nowak-Flück D, Stembridge M, Ainslie P, McManus AM. Dynamic onset response of the internal carotid artery to hypercapnia is blunted in children compared with adults. Physiological Reports, 2022; 10(16):e15406.
  6. Rieger MG, Algaze I, Rodriguez-Vasquez A, Smith KJ, Stembridge M, Smith B, Radom-Aizik S, McManus AM. Kids with altitude: acute mountain sickness and changes in body mass and total body water in children travelling to 3800 m. Wilderness & Environmental Medicine. 2022 Mar; 33(1):33-42. doi: 10.1016/j.wem.2021.11.001.
  7. Hesketh K, Low J, Andrews RC, Jones CA, Jones H, Jung ME, Little JP, Mateus C, Pulsford RM, Singer J, Sprung VS, McManus AM, Cocks M. Mobile health biometrics to enhance exercise and physical activity adherence in Type 2 Diabetes (MOTIVATE-T2D): Protocol for a feasibility randomised controlled trial.  British Medical Journal Open, 2021; 26;11(11): e052563.
  8. Tallon CM, Smith KJ, Nowak-Flück D, Koziol AV, Rieger MG, Lutes LD, Green DJ, Tremblay MS, Ainslie PN, McManus AM. The influence of sex and maturation on carotid and vertebral artery hemodynamics and associations with free-living (in)activity in 6-17 year-olds. Journal of Applied Physiology, 2021; 131(5):1575-1583.
  9. Tallon CM, Barker AR, Nowak-Flück D, Ainslie PN, McManus AM. The influence of age and sex on cerebrovascular reactivity and ventilatory response to hypercapnia in children and adults. Experimental Physiology, 2020; 105(7):1090-1101.

 

  1. Ruggiero L, Harrison SWD, Rice CL, McNeil CJ (2022). Neuromuscular fatigability at high altitude: Lowlanders with acute and chronic exposure, and native highlanders. Acta Physiologica. 234(4):e137888 https://pubmed.ncbi.nlm.nih.gov/35007386/ DOI: https://doi.org/10.1111/apha.13788
  2. Ruggiero L, Yacyshyn AF, Nettleton J, McNeil CJ (2018). UBC-Nepal Expedition: acclimatization to high-altitude increases spinal motoneurone excitability during fatigue in humans. The Journal of Physiology. 596(15):3327-3339 https://pubmed.ncbi.nlm.nih.gov/29130497/ DOI: https://doi.org/10.1113/jp274872
  3. Yacyshyn AF, McNeil CJ (2022). Intrinsic neuromuscular fatigability in humans: the critical role of stimulus frequency. Exercise and Sport Sciences Reviews. 50(2):97-103 https://pubmed.ncbi.nlm.nih.gov/35025843/ DOI: https://doi.org/10.1249/JES.0000000000000283
  4. Amann M, Sidhu SK, McNeil CJ, Gandevia SC (2022). Critical considerations on the contribution of the corticospinal pathway to central fatigue. The Journal of Physiology. 600(24):5203-5214 https://pubmed.ncbi.nlm.nih.gov/36326193/ DOI: https://doi.org/10.1113/JP282564
  5. Magnuson JR, Dalton BH, McNeil CJ (2023). The orderly recruitment of motor units may be modified when a muscle is acting as an antagonist. Journal of Applied Physiology. 135(3):519-526 https://pubmed.ncbi.nlm.nih.gov/37439237/ DOI: https://doi.org/10.1152/japplphysiol.00203.2023
  6. Ruggiero L, Hoiland RL, Hansen AB, Ainslie PN, McNeil CJ (2020). High-altitude acclimatization improves recovery from muscle fatigue. Medicine & Science in Sports & Exercise. 52(1):161-169 https://pubmed.ncbi.nlm.nih.gov/31343519/ DOI: https://doi.org/10.1249/mss.0000000000002100
  7. Yacyshyn AF, McNeil CJ (2020). The sexes do not differ for neural responses to submaximal elbow extensor fatigue. Medicine & Science in Sports & Exercise. 52(9):1992-2001 https://pubmed.ncbi.nlm.nih.gov/32195769/ DOI: https://doi.org/10.1249/mss.0000000000002342
  8. Bruce CD, Magnuson JR, McNeil CJ (2023). Voluntary activation does not differ when using two different methods to determine transcranial magnetic stimulator output. Journal of Neurophysiology 130(4):925-930 https://pubmed.ncbi.nlm.nih.gov/37671448/ DOI: https://doi.org/10.1152/jn.00132.2023
  9. Bruce CD, Ruggiero L, Dix GU, Cotton PD, McNeil CJ (2021). Females and males do not differ for fatigability, muscle damage and magnitude of the repeated bout effect following maximal eccentric contractions. Applied Physiology, Nutrition and Metabolism. 46(3):238-246 https://pubmed.ncbi.nlm.nih.gov/32937087/ DOI: https://doi.org/10.1139/apnm-2020-0516
  10. Magnuson JR, Dalton BH, McNeil CJ (In Press). Differential modulation of motor unit behaviour when a fatiguing contraction is matched for torque vs. EMG. Medicine & Science in Sports & Exercise. https://pubmed.ncbi.nlm.nih.gov/38595197/ DOI:10.1249/MSS.0000000000003434
  1. Curry BA, Drane AL, Atencia R, Feltrer Y, Calvi T, Milnes EL, Moittié S, Weigold A, Knauf-Witzens T, Sawung Kusuma A, Howatson G, Palmer C, Stembridge MR, Gorzynski JE, Eves ND, Dawkins TG, Shave RE.Left ventricular trabeculation in Hominidae: divergence of the human cardiac phenotype. Commun Biol. 2024 Jun 14;7(1):682. doi: 10.1038/s42003-024-06280-9.
    PMID: 38877299 Free PMC article.
  2. Perkins DR, Talbot JS, Lord RN, Dawkins TG, Baggish AL, Zaidi A, Uzun O, Mackintosh KA, McNarry MA, Cooper SM, Lloyd RS, Oliver JL, Shave RE, Stembridge M.Adaptation of Left Ventricular Twist Mechanics in Exercise-Trained Children Is Only Evident after the Adolescent Growth Spurt.
    J Am Soc Echocardiogr. 2024 May;37(5):538-549. doi: 10.1016/j.echo.2023.11.024. Epub 2023 Dec 11.
    PMID: 38056578
  3. McGregor G, Powell R, Begg B, Birkett ST, Nichols S, Ennis S, McGuire S, Prosser J, Fiassam O, Hee SW, Hamborg T, Banerjee P, Hartfiel N, Charles JM, Edwards RT, Drane A, Ali D, Osman F, He H, Lachlan T, Haykowsky MJ, Ingle L, Shave R.High-intensity interval training in cardiac rehabilitation: a multi-centre randomized controlled trial.
    Eur J Prev Cardiol. 2023 Jul 12;30(9):745-755. doi: 10.1093/eurjpc/zwad039.
    PMID: 36753063 Clinical Trial.
  4. Dawkins Tony G, Curry Bryony A, Drane Aimee L, Lord Rachel N, Richards Cory, Brown Megan, Pugh Christopher J A, Lodge Freya, Yousef Zaheer, Stembridge Michael, Shave Rob E. (2020, August). Stimulus-specific functional remodeling of the left ventricle in endurance and resistance-trained men.American journal of physiology. Heart and circulatory physiology, 319(3), H632-H641. https://pubmed.ncbi.nlm.nih.gov/32772543/ DOI: https://doi.org/10.1152/ajpheart.00233.2020
  5. Shave Robert E, Lieberman Daniel E, Drane Aimee L, Brown Marcel G, Batterham Alan M, Worthington Steven, Atencia Rebeca, Feltrer Yedra, Neary Jennifer, Weiner Rory B, Wasfy Meagan M, Baggish Aaron L. (2019, September 16). Selection of endurance capabilities and the trade-off between pressure and volume in the evolution of the human heart.Proceedings of the National Academy of Sciences of the United States of America, 116(40), 19905-19910. https://www.pnas.org/content/116/40/19905 DOI: https://doi.org/10.1073/pnas.1906902116
  6. Drane Aimee L, Atencia Rebeca, Cooper Stephen-Mark, Rodriguez Pablo, Sanchez Carlos, Simcox Sarah, Feltrer Yedra, Peck Bruce, Eng Jaclyn, Moittie Sophie, Unwin Steve, Howatson Glyn, Oxborough David, Stembridge Mike R, Shave Rob E. (2019, June). Cardiac structure and function characterized across age groups and between sexes in healthy wild-born captive chimpanzees (Pan Troglodytes) living in sanctuaries.American journal of veterinary research, 80(6), 547-557. https://pubmed.ncbi.nlm.nih.gov/31140849/ DOI: https://doi.org/10.2460/ajvr.80.6.547
  7. Stembridge Mike, Ainslie Philip N, Boulet Lindsey M, Anholm James, Subedi Prajan, Tymko Michael M, Willie Christopher K, Cooper Stephen-Mark, Shave Rob. (2018, May 28). The independent effects of hypovolaemia and pulmonary vasoconstriction on ventricular function and exercise capacity during acclimatisation to 3800 m.The Journal of physiology. https://pubmed.ncbi.nlm.nih.gov/29808473/ DOI: https://doi.org/10.1113/jp275278
  8. Stöhr EJ, McDonnell B, Thompson J, Stone K, Bull T, Houston R, Cockcroft J, Shave R. (2012, May). Left ventricular mechanics in humans with high aerobic fitness: adaptation independent of structural remodelling, arterial haemodynamics and heart rate.J Physiol, 590(1), 2107-19. https://pubmed.ncbi.nlm.nih.gov/22431336/ DOI: https://doi.org/10.1113/jphysiol.2012.227850
  9. Shave R, Baggish A, George K, Wood M, Scharhag J, Whyte G, Gaze D, Thompson PD. (2010, July). Exercise-induced cardiac troponin elevation: evidence, mechanisms, and implications.J Am Coll Cardiol, 56(3), 169-76. https://pubmed.ncbi.nlm.nih.gov/20620736/ DOI: https://doi.org/10.1016/j.jacc.2010.03.037
  10. Middleton N, George K, Whyte G, Gaze D, Collinson P, Shave R. (2008, November). Cardiac troponin T release is stimulated by endurance exercise in healthy humans.J Am Coll Cardiol, 25(52), 1813-4. https://pubmed.ncbi.nlm.nih.gov/19022162/ DOI: https://doi.org/10.1016/j.jacc.2008.03.069
  1. Williams AM, Manouchehri N, Erskine E, Tauh K, So K, Shortt K, Webster M, Fisk S, Billingsley A, Munro A, Tigchelaar S, Streijger F, Kim KT, Kwon BK, West CR. Cardio-centric hemodynamic management improves spinal cord oxygenation and mitigates hemorrhage in acute spinal cord injury. Nat Commun. 2020 Oct 15;11(1):5209. https://www.researchgate.net/publication/345395079_Cardio-centric_hemodynamic_management_improves_spinal_cord_oxygenation_and_mitigates_hemorrhage_in_acute_spinal_cord_injury DOI: https://www.nature.com/articles/s41467-020-18905-8
  2. West CR, Phillips AA, Squair JW, Williams AM, Walter M, Lam T, Krassioukov AV. Association of Epidural Stimulation With Cardiovascular Function in an Individual With Spinal Cord Injury. JAMA Neurol. 2018 May 1;75(5):630-632. https://pubmed.ncbi.nlm.nih.gov/29459943/ DOI: https://doi.org/10.1001/jamaneurol.2017.5055
  3. Squair JW, Bélanger LM, Tsang A, Ritchie L, Mac-Thiong JM, Parent S, Christie S, Bailey C, Dhall S, Street J, Ailon T, Paquette S, Dea N, Fisher CG, Dvorak MF, West CR, Kwon BK. Spinal cord perfusion pressure predicts neurologic recovery in acute spinal cord injury. Neurology. 2017 Oct 17;89(16):1660-1667 https://pubmed.ncbi.nlm.nih.gov/28916535/ DOI: https://doi.org/10.1212/wnl.0000000000004519
  4. Squair JW, Bélanger LM, Tsang A, Ritchie L, Mac-Thiong JM, Parent S, Christie S, Bailey C, Dhall S, Charest-Morin R, Street J, Ailon T, Paquette S, Dea N, Fisher CG, Dvorak MF, West CR, Kwon BK. Empirical targets for acute hemodynamic management of individuals with spinal cord injury. Neurology. 2019 Sep 17;93(12):e1205-e1211. https://pubmed.ncbi.nlm.nih.gov/31409736/ DOI: https://doi.org/10.1212/wnl.0000000000008125
  5. West CR, Squair JW, McCracken L, Currie KD, Somvanshi R, Yuen V, Phillips AA, Kumar U, McNeill JH, Krassioukov AV. Cardiac Consequences of Autonomic Dysreflexia in Spinal Cord Injury. Hypertension. 2016 Nov;68(5):1281-1289. https://pubmed.ncbi.nlm.nih.gov/27698067/ DOI: https://doi.org/10.1161/hypertensionaha.116.07919
  6. West CR, Poormasjedi-Meibod MS, Manouchehri N, Williams AM, Erskine EL, Webster M, Fisk S, Morrison C, Short K, So K, Cheung A, Streijger F, Kwon BK. A porcine model for studying the cardiovascular consequences of high-thoracic spinal cord injury. J Physiol. 2020 Mar;598(5):929-942. https://pubmed.ncbi.nlm.nih.gov/31876952/ DOI: https://doi.org/10.1113/jp278451
  7. Gee CM, Williams AM, Sheel AW, Eves ND, West CR. Respiratory muscle training in athletes with cervical spinal cord injury: effects on cardiopulmonary function and exercise capacity. J Physiol. 2019 Jul;597(14):3673-3685. https://pubmed.ncbi.nlm.nih.gov/31115056/ DOI: https://doi.org/10.1113/jp277943
  8. Williams AM, Gee CM, Voss C, West CR. Cardiac consequences of spinal cord injury: systematic review and meta-analysis. Heart. 2019 Feb;105(3):217-225. https://pubmed.ncbi.nlm.nih.gov/30262456/ DOI: https://doi.org/10.1136/heartjnl-2018-313585
  9. DeVeau KM, Harman KA, Squair JW, Krassioukov AV, Magnuson DSK, West CR. A comparison of passive hindlimb cycling and active upper-limb exercise provides new insights into systolic dysfunction after spinal cord injury. Am J Physiol Heart Circ Physiol. 2017 Nov 1;313(5):H861-H870. https://pubmed.ncbi.nlm.nih.gov/28710067/ DOI: https://doi.org/10.1152/ajpheart.00046.2017
  10. Gee CM, Lacroix MA, Pethick WA, Côté P, Stellingwerff T, West CR. Cardiovascular responses to heat acclimatisation in athletes with spinal cord injury. J Sci Med Sport. 2021 Jan 31:S1440-2440(21)00019-0. https://www.researchgate.net/publication/348925825_Cardiovascular_responses_to_heat_acclimatisation_in_athletes_with_spinal_cord_injury DOI: http://dx.doi.org/10.1016/j.jsams.2021.01.007

Research collaborations between Centre affiliates